Jean-Michel Brunel Selected Research

squalamine

11/2019	A squalamine derivative, NV669, as a novel PTP1B inhibitor: in vitro and in vivo effects on pancreatic and hepatic tumor growth.
3/2019	Anti-persister activity of squalamine against Acinetobacter baumannii.
4/2015	A double-blind randomized placebo-controlled clinical trial of squalamine ointment for tinea capitis treatment.
10/2012	Antibacterial efficacy of inhaled squalamine in a rat model of chronic Pseudomonas aeruginosa pneumonia.

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Jean-Michel Brunel Research Topics

Disease

6	Infections 03/2024 - 08/2012
4	Neoplasms (Cancer) 11/2019 - 01/2012
3	Parkinson Disease (Parkinson's Disease) 03/2024 - 01/2022
2	Liver Neoplasms (Liver Cancer) 11/2019 - 01/2018
2	Breast Neoplasms (Breast Cancer) 01/2018 - 01/2012
2	Pneumonia (Pneumonitis) 10/2013 - 10/2012
1	Neuroinflammatory Diseases 03/2024
1	Synucleinopathies 01/2022
1	Bacterial Infections (Bacterial Infection) 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 11/2019
1	Adenocarcinoma 11/2019
1	Starvation 03/2019
1	Septic Shock (Toxic Shock Syndrome) 10/2018
1	Heart Failure 10/2018
1	Tinea Capitis 04/2015
1	Tinea (Ringworm) 04/2015
1	Necrosis 03/2013
1	Rheumatoid Arthritis 01/2012

Drug/Important Bio-Agent (IBA)

5	Colistin (Coly-Mycin)FDA Link 01/2021 - 08/2012
4	Anti-Bacterial Agents (Antibiotics)IBA 03/2024 - 01/2021
4	squalamineIBA 11/2019 - 10/2012
2	Tetracycline (Achromycin)FDA LinkGeneric 03/2024 - 02/2023
2	Doxycycline (Periostat)FDA LinkGeneric 03/2024 - 02/2023
2	AerosolsIBA 01/2021 - 10/2012
1	TetracyclinesIBA 03/2024
1	AntioxidantsIBA 03/2024
1	SynucleinsIBA 03/2024
1	2',3'-dideoxy-5-methylcytidineIBA 01/2022
1	Volatile Oils (Essential Oils)IBA 01/2021
1	AminoglycosidesIBA 01/2021
1	Antineoplastic Agents (Antineoplastics)IBA 11/2019
1	CyclinsIBA 11/2019
1	Ciprofloxacin (Cipro)FDA LinkGeneric 03/2019
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2018
1	Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA 10/2018
1	Protein Isoforms (Isoforms)IBA 01/2018
1	Docetaxel (Taxotere)FDA Link 01/2018
1	Liposomes (Liposome)IBA 01/2018
1	Trastuzumab (Herceptin)FDA Link 01/2018
1	Ointments (Pastes)IBA 04/2015
1	Proteins (Proteins, Gene)FDA Link 03/2013
1	CytokinesIBA 03/2013
1	Saline SolutionIBA 10/2012
1	Phenobarbital (Luminal)FDA Link 01/2012
1	thiamorpholine (thiomorpholine)IBA 01/2012
1	Metalloproteases (Metalloproteinases)IBA 01/2012
1	apratastatIBA 01/2012

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 01/2012
1	Therapeutics 01/2012